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Multifaceted role of EZH2 in breast and prostate tumorigenesis: Epigenetics and beyond

Overexpression of EZH2 and other PRC2 subunits, such as SUZ12, is associated with tumor progression and poor prognosis in several human malignancies. Nevertheless, the underlying mechanisms driving aberrant EZH2 expression are poorly understood. This review provides molecular insights into the essen...

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Detalhes bibliográficos
Main Authors: Deb, Gauri, Thakur, Vijay S., Gupta, Sanjay
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741216/
https://ncbi.nlm.nih.gov/pubmed/23644490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.24532
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