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Direct activation of Foxo3 by tumor suppressors p53 and p73 is disrupted during liver regeneration in mice
The p53-family of proteins regulates expression of target genes that promote cell cycle arrest and apoptosis, which may be linked to cellular growth control as well as tumor suppression. Within the p53-family, p53 and TA-p73 have hepatic-specific functions in development and tumor suppression. Here,...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3741038/ https://ncbi.nlm.nih.gov/pubmed/20564353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23746 |
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