Characterizing the emergence and persistence of drug resistant mutations in HIV-1 subtype C infections using 454 ultra deep pyrosequencing

BACKGROUND: The role of HIV-1 RNA in the emergence of resistance to antiretroviral therapies (ARTs) is well documented while less is known about the role of historical viruses stored in the proviral DNA. The primary focus of this work was to characterize the genetic diversity and evolution of HIV dr...

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Main Authors: Bansode, Vijay, McCormack, Grace P, Crampin, Amelia C, Ngwira, Bagrey, Shrestha, Ram K, French, Neil, Glynn, Judith R, Travers, Simon A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740783/
https://ncbi.nlm.nih.gov/pubmed/23363532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-13-52
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