Response classification based on a minimal model of glioblastoma growth is prognostic for clinical outcomes and distinguishes progression from pseudoprogression

Glioblastoma multiforme (GBM) is the most aggressive type of primary brain tumor. GBM growth dynamics vary widely across patients, making it difficult to accurately gauge their response to treatment. We developed a model-based metric of therapy response called Days Gained that accounts for this hete...

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Main Authors: Neal, Maxwell Lewis, Trister, Andrew D., Ahn, Sunyoung, Baldock, Anne, Bridge, Carly A., Guyman, Laura, Lange, Jordan, Sodt, Rita, Cloke, Tyler, Lai, Albert, Cloughesy, Timothy F., Mrugala, Maciej M., Rockhill, Jason K., Rockne, Russell C., Swanson, Kristin R.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740772/
https://ncbi.nlm.nih.gov/pubmed/23400596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3588
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