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Response classification based on a minimal model of glioblastoma growth is prognostic for clinical outcomes and distinguishes progression from pseudoprogression

Glioblastoma multiforme (GBM) is the most aggressive type of primary brain tumor. GBM growth dynamics vary widely across patients, making it difficult to accurately gauge their response to treatment. We developed a model-based metric of therapy response called Days Gained that accounts for this hete...

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Detalhes bibliográficos
Main Authors: Neal, Maxwell Lewis, Trister, Andrew D., Ahn, Sunyoung, Baldock, Anne, Bridge, Carly A., Guyman, Laura, Lange, Jordan, Sodt, Rita, Cloke, Tyler, Lai, Albert, Cloughesy, Timothy F., Mrugala, Maciej M., Rockhill, Jason K., Rockne, Russell C., Swanson, Kristin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740772/
https://ncbi.nlm.nih.gov/pubmed/23400596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-3588
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