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Data-based filtering for replicated high-throughput transcriptome sequencing experiments

Motivation: RNA sequencing is now widely performed to study differential expression among experimental conditions. As tests are performed on a large number of genes, stringent false-discovery rate control is required at the expense of detection power. Ad hoc filtering techniques are regularly used t...

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Détails bibliographiques
Auteurs principaux: Rau, Andrea, Gallopin, Mélina, Celeux, Gilles, Jaffrézic, Florence
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740625/
https://ncbi.nlm.nih.gov/pubmed/23821648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt350
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