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A hierarchical poisson log-normal model for network inference from RNA sequencing data.

Gene network inference from transcriptomic data is an important methodological challenge and a key aspect of systems biology. Although several methods have been proposed to infer networks from microarray data, there is a need for inference methods able to model RNA-seq data, which are count-based an...

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Detalhes bibliográficos
Main Authors: Mélina Gallopin, Andrea Rau, Florence Jaffrézic
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3798343?pdf=render
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