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Loss of Cholinergic Phenotype in Septohippocampal Projection Neurons: Relation to Brain Versus Peripheral IL-2 Deficiency

In the peripheral immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. IL-2 knockout (IL-2KO) mice develop spontaneous autoimmunity characterized by increased T cell trafficking to multiple organs. The IL-2 gene is also expressed in the brai...

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Detalhes bibliográficos
Main Authors: Meola, Danielle M., Huang, Zhi, King, Michael, Petitto, John M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740576/
https://ncbi.nlm.nih.gov/pubmed/23416322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2013.01.054
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