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Dissecting the Effects of Endogenous Brain IL-2 and Normal Versus Autoreactive T Lymphocytes on Microglial Responsivness and T Cell Trafficking in Response to Axonal Injury
IL-2 is essential for T-helper regulatory (Treg) cell function and self-tolerance, and dysregulation of both endogenous brain and peripheral IL-2 gene expression may have important implications for neuronal injury and repair. We used an experimental approach combining mouse congenic breeding and imm...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482546/ https://ncbi.nlm.nih.gov/pubmed/22922129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.018 |
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