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Dissecting the Effects of Endogenous Brain IL-2 and Normal Versus Autoreactive T Lymphocytes on Microglial Responsivness and T Cell Trafficking in Response to Axonal Injury

IL-2 is essential for T-helper regulatory (Treg) cell function and self-tolerance, and dysregulation of both endogenous brain and peripheral IL-2 gene expression may have important implications for neuronal injury and repair. We used an experimental approach combining mouse congenic breeding and imm...

詳細記述

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書誌詳細
主要な著者: Huang, Zhi, Meola, Danielle, Petitto, John M.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482546/
https://ncbi.nlm.nih.gov/pubmed/22922129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2012.08.018
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