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Association of Environmental and Genetic Factors and Gene-Environment Interactions with Risk of Developing Rheumatoid Arthritis

BACKGROUND: We developed RA risk models based on validated environmental factors (E), genetic risk scores (GRS), and gene-environment interactions (GEI) to identify factors that can improve accuracy and reclassification. METHODS: Models including E, GRS, GEI were developed among 317 Caucasian seropo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Karlson, Elizabeth W., Ding, Bo, Keenan, Brendan T., Liao, Katherine, Costenbader, Karen H., Klareskog, Lars, Alfredsson, Lars, Chibnik, Lori B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740546/
https://ncbi.nlm.nih.gov/pubmed/23495093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acr.22005
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