Genetic Risk Score Predicting Risk of Rheumatoid Arthritis Phenotypes and Age of Symptom Onset

BACKGROUND: Cumulative genetic profiles can help identify individuals at high-risk for developing RA. We examined the impact of 39 validated genetic risk alleles on the risk of RA phenotypes characterized by serologic and erosive status. METHODS/PRINCIPAL FINDINGS: We evaluated single nucleotide pol...

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Detalhes bibliográficos
Main Authors: Chibnik, Lori B., Keenan, Brendan T., Cui, Jing, Liao, Katherine P., Costenbader, Karen H., Plenge, Robert M., Karlson, Elizabeth W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171415/
https://ncbi.nlm.nih.gov/pubmed/21931699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024380
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