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Molecular Origins of Cofilin-linked Changes in Actin Filament Mechanics

The actin regulatory protein cofilin plays a central role in actin assembly dynamics by severing filaments and increasing the concentration of ends from which subunits add and dissociate. Cofilin binding modifies the average structure and mechanical properties of actin filaments, thereby promoting f...

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Autors principals: Fan, Jun, Saunders, Marissa G., Haddadian, Esmael J., Freed, Karl F., De La Cruz, Enrique M., Voth, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740545/
https://ncbi.nlm.nih.gov/pubmed/23352932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.01.020
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