Elevated Intracellular Calcium Stimulates NHE3 Activity by an IKEPP (NHERF4) Dependent Mechanism

The ileal brush border (BB) contains four evolutionarily related multi-PDZ domain proteins including NHERF1, NHERF2, PDZK1 (NHERF3) and IKEPP (NHERF4). Why multiple related PDZ proteins are in a similar location in the same cell is unknown. However, some specificity in regulation of NHE3 activity ha...

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Autors principals: Zachos, Nicholas C., Hodson, Caleb, Kovbasnjuk, Olga, Li, Xuhang, Thelin, William R., Cha, Boyoung, Milgram, Sharon, Donowitz, Mark
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2008
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740532/
https://ncbi.nlm.nih.gov/pubmed/19088451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000185553
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