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Synthesis of the calcilytic ligand NPS 2143

(R)-3 (NPS 2143) is a negative allosteric modulator of the human calcium-sensing receptor (CaSR) and as such represents an important pharmacological tool compound for studying the CaSR. Herein, we disclose for the first time a complete experimental description, detailed characterisation and assessme...

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Bibliografske podrobnosti
Main Authors: Johansson, Henrik, Cailly, Thomas, Rojas Bie Thomsen, Alex, Bräuner-Osborne, Hans, Sejer Pedersen, Daniel
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740522/
https://ncbi.nlm.nih.gov/pubmed/23946832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.154
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