Assessment of the Prognostic Value of Two Common Variants of BRCA1 and BRCA2 Genes in Ovarian Cancer Patients Treated with Cisplatin and Paclitaxel: A Gynecologic Oncology Group Study

Purpose: BRCA1/BRCA2 germline mutations appear to enhance the platinum-sensitivity, but little is known about the prognostic relevance of polymorphisms in BRCA1/BRCA2 in epithelial ovarian cancer (EOC). This study evaluated whether common variants of BRCA1/BRCA2 are associated with progression-free...

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Autori principali: Tian, Chunqiao Q., Darcy, Kathleen M., Krivak, Thomas C., DeLoia, Julie A., Armstrong, Deborah, Davis, Warren, Zhao, Hua, Moysich, Kirsten, Ambrosone, Christine B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740480/
https://ncbi.nlm.nih.gov/pubmed/23964347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2013.00206
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