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A Disintegrin and Metalloproteinase-12 (ADAM12): Function, Roles in Disease Progression, and Clinical Implications

BACKGROUND: A disintegrin and metalloproteinase-12 (ADAM12) is a member of the greater ADAM family of enzymes: these are multifunctional, generally membrane-bound, zinc proteases for which there are forty genes known (21 of these appearing in humans). ADAM12 has been implicated in the pathogenesis o...

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Autors principals: Nyren-Erickson, Erin K., Jones, Justin M., Srivastava, D. K., Mallik, Sanku
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3740046/
https://ncbi.nlm.nih.gov/pubmed/23680494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.05.011
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