5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: Contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKβ/IκB-α/NF-κB pathway, and proinflammatory cytokine formation

Eitemau Tebyg

• Effects of 5,14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKKβ/IκB-α/NF-κB pathway and circulating miR-150, miR-223, and miR-297 levels in a rat model of septic shock
  gan: Sari, A. Nihal, et al.
  Cyhoeddwyd: (2014)
• A Synthetic Analogue of 20-HETE, 5,14-HEDGE, Reverses Endotoxin-Induced Hypotension via Increased 20-HETE Levels Associated with Decreased iNOS Protein Expression and Vasodilator Prostanoid Production in Rats
  gan: Cuez, Tuba, et al.
  Cyhoeddwyd: (2009)
• Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock()
  gan: Tunctan, Bahar, et al.
  Cyhoeddwyd: (2013)
• Contribution of Vasoactive Eicosanoids and Nitric Oxide Production to the Effect of Selective Cyclooxygenase-2 Inhibitor, NS-398, on Endotoxin-Induced Hypotension in Rats
  gan: Tunctan, Bahar, et al.
  Cyhoeddwyd: (2010)
• NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite
  gan: Tunctan, Bahar, et al.
  Cyhoeddwyd: (2012)