Smoking in Asthma Is Associated with Elevated Levels of Corticosteroid Resistant Sputum Cytokines—An Exploratory Study

BACKGROUND: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear. Whilst cytokines can induce corticosteroid insensitivi...

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Autori principali: Spears, Mark, McSharry, Charles, Chaudhuri, Rekha, Weir, Christopher J., de Wet, Carl, Thomson, Neil C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739804/
https://ncbi.nlm.nih.gov/pubmed/23951170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071460
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