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Smoking in Asthma Is Associated with Elevated Levels of Corticosteroid Resistant Sputum Cytokines—An Exploratory Study

BACKGROUND: Current cigarette smoking is associated with reduced acute responses to corticosteroids and worse clinical outcomes in stable chronic asthma. The mechanism by which current smoking promotes this altered behavior is currently unclear. Whilst cytokines can induce corticosteroid insensitivi...

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Main Authors: Spears, Mark, McSharry, Charles, Chaudhuri, Rekha, Weir, Christopher J., de Wet, Carl, Thomson, Neil C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739804/
https://ncbi.nlm.nih.gov/pubmed/23951170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071460
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