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IL-7 Promotes T(H)1 Cell Differentiation and Its Level in Serum Predicts Response to Interferon-β in Multiple Sclerosis
The interleukin-7 receptor α chain (IL-7Rα) gene was identified as a top non–major histocompatibility complex–linked risk locus for multiple sclerosis (MS). Recently, we showed that a T helper 1 (TH1)–driven, but not a TH17-driven, form of MS exhibited a good clinical response to interferon-β (IFN-β...
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Główni autorzy: | , , , , , , , , , , , , , , , |
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Format: | Artigo |
Język: | Inglês |
Wydane: |
2011
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3739690/ https://ncbi.nlm.nih.gov/pubmed/21795588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002400 |
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