IL-7 Promotes T(H)1 Cell Differentiation and Its Level in Serum Predicts Response to Interferon-β in Multiple Sclerosis

The interleukin-7 receptor α chain (IL-7Rα) gene was identified as a top non–major histocompatibility complex–linked risk locus for multiple sclerosis (MS). Recently, we showed that a T helper 1 (TH1)–driven, but not a TH17-driven, form of MS exhibited a good clinical response to interferon-β (IFN-β...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Lee, Li-Fen, Axtell, Robert, Tu, Guang Huan, Logronio, Kathryn, Dilley, Jeanette, Yu, Jessica, Rickert, Mathias, Han, Bora, Evering, Winston, Walker, Michael G., Shi, Jing, de Jong, Brigit A., Killestein, Joep, Polman, Chris H., Steinman, Lawrence, Lin, John C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739690/
https://ncbi.nlm.nih.gov/pubmed/21795588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002400
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi