IL-7 Promotes T(H)1 Cell Differentiation and Its Level in Serum Predicts Response to Interferon-β in Multiple Sclerosis

The interleukin-7 receptor α chain (IL-7Rα) gene was identified as a top non–major histocompatibility complex–linked risk locus for multiple sclerosis (MS). Recently, we showed that a T helper 1 (TH1)–driven, but not a TH17-driven, form of MS exhibited a good clinical response to interferon-β (IFN-β...

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Bibliografski detalji
Glavni autori: Lee, Li-Fen, Axtell, Robert, Tu, Guang Huan, Logronio, Kathryn, Dilley, Jeanette, Yu, Jessica, Rickert, Mathias, Han, Bora, Evering, Winston, Walker, Michael G., Shi, Jing, de Jong, Brigit A., Killestein, Joep, Polman, Chris H., Steinman, Lawrence, Lin, John C.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739690/
https://ncbi.nlm.nih.gov/pubmed/21795588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002400
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