The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8p

BACKGROUND: The function of the fission yeast cullins Pcu1p and Pcu4p requires modification by the ubiquitin-related peptide Ned8p. A recent report by Lyapina et al. shows that the COP9/signalosome (CSN), a multifunctional eight subunit complex, regulates Ned8p modification of Pcu1p. Disruption of c...

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Main Authors: Zhou, Chunshui, Seibert, Volker, Geyer, Rory, Rhee, Edward, Lyapina, Svetlana, Cope, Greg, Deshaies, Raymond J, Wolf, Dieter A
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2001
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC37391/
https://ncbi.nlm.nih.gov/pubmed/11504566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-2-7
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