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Differential Response in Downstream Processing of CHO Cells Grown Under Mild Hypothermic Conditions
The manufacture of complex therapeutic proteins using mammalian cells is well established, with several strategies developed to improve productivity. The application of sustained mild hypothermic conditions during culture has been associated with increases in product titer and improved product quali...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738919/ https://ncbi.nlm.nih.gov/pubmed/23636936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.1726 |
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