The C. elegans DSB-2 Protein Reveals a Regulatory Network that Controls Competence for Meiotic DSB Formation and Promotes Crossover Assurance

For most organisms, chromosome segregation during meiosis relies on deliberate induction of DNA double-strand breaks (DSBs) and repair of a subset of these DSBs as inter-homolog crossovers (COs). However, timing and levels of DSB formation must be tightly controlled to avoid jeopardizing genome inte...

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Hauptverfasser: Rosu, Simona, Zawadzki, Karl A., Stamper, Ericca L., Libuda, Diana E., Reese, Angela L., Dernburg, Abby F., Villeneuve, Anne M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738457/
https://ncbi.nlm.nih.gov/pubmed/23950729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003674
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