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Identification of DSB-1, a Protein Required for Initiation of Meiotic Recombination in Caenorhabditis elegans, Illuminates a Crossover Assurance Checkpoint

Meiotic recombination, an essential aspect of sexual reproduction, is initiated by programmed DNA double-strand breaks (DSBs). DSBs are catalyzed by the widely-conserved Spo11 enzyme; however, the activity of Spo11 is regulated by additional factors that are poorly conserved through evolution. To ex...

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Detalhes bibliográficos
Main Authors: Stamper, Ericca L., Rodenbusch, Stacia E., Rosu, Simona, Ahringer, Julie, Villeneuve, Anne M., Dernburg, Abby F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749324/
https://ncbi.nlm.nih.gov/pubmed/23990794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003679
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