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Electronic Measurements of Single-Molecule Catalysis by cAMP-Dependent Protein Kinase A
Single-molecule studies of enzymes open a window into their dynamics and kinetics. A single molecule of the catalytic domain of cAMP-dependent protein kinase (PKA) was attached to a single-walled carbon nanotube device for long duration monitoring. The electronic recording clearly resolves substrate...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738266/ https://ncbi.nlm.nih.gov/pubmed/23631749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311604j |
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