Electronic Measurements of Single-Molecule Processing by DNA Polymerase I (Klenow Fragment)

Bioconjugating single molecules of the Klenow fragment of DNA polymerase I into electronic nanocircuits allowed electrical recordings of enzymatic function and dynamic variability with the resolution of individual nucleotide incorporation events. Continuous recordings of DNA polymerase processing mu...

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Hauptverfasser: Olsen, Tivoli J., Choi, Yongki, Sims, Patrick C., Gul, O. Tolga, Corso, Brad L., Dong, Chengjun, Brown, William A., Collins, Philip G., Weiss, Gregory A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3738269/
https://ncbi.nlm.nih.gov/pubmed/23631761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311603r
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