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Inverted Low-Copy Repeats and Genome Instability—A Genome-Wide Analysis
Inverse paralogous low-copy repeats (IP-LCRs) can cause genome instability by nonallelic homologous recombination (NAHR)-mediated balanced inversions. When disrupting a dosage-sensitive gene(s), balanced inversions can lead to abnormal phenotypes. We delineated the genome-wide distribution of IP-LCR...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738003/ https://ncbi.nlm.nih.gov/pubmed/22965494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.22217 |
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