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Chaperone-assisted proteostasis is essential for mechanotransduction in mammalian cells

Maintaining the dynamic proteome of a living cell in the face of an ever-changing environment depends on a fine-tuned balance of protein synthesis and protein degradation. Molecular chaperones exert key functions during protein homeostasis (proteostasis). They associate with nonnative client protein...

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Autors principals: Ulbricht, Anna, Arndt, Verena, Höhfeld, Jörg
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737759/
https://ncbi.nlm.nih.gov/pubmed/23986815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.24925
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