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Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation

Macropinocytosis, a fluid-phase endocytosis, is a crucial pathway for antigen uptake and presentation in macrophages. We attempted to characterise the activation and deactivation of a small GTPase molecular switch, Rac1, in macropinocytosis using microscopic photo-manipulation. Expression of genetic...

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Hlavní autoři: Fujii, Makoto, Kawai, Katsuhisa, Egami, Youhei, Araki, Nobukazu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737501/
https://ncbi.nlm.nih.gov/pubmed/23924974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02385
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