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Dissecting the roles of Rac1 activation and deactivation in macropinocytosis using microscopic photo-manipulation
Macropinocytosis, a fluid-phase endocytosis, is a crucial pathway for antigen uptake and presentation in macrophages. We attempted to characterise the activation and deactivation of a small GTPase molecular switch, Rac1, in macropinocytosis using microscopic photo-manipulation. Expression of genetic...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3737501/ https://ncbi.nlm.nih.gov/pubmed/23924974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02385 |
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