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Design and synthesis of glycoprotein-based multivalent glyco-ligands for influenza hemagglutinin and human galectin-3

We report a facile synthesis of glycoprotein-based glyco-ligands and their binding with influenza hemagglutinin and human galectin-3. Human serum albumin (HSA) was used as the scaffold and an Asn-linked complex type N-glycan prepared from chicken eggs was used as the glycan building block. It was fo...

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Detalhes bibliográficos
Main Authors: Wang, Helen, Huang, Wei, Orwenyo, Jared, Banerjee, Aditi, Vasta, Gerardo R., Wang, Lai-Xi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737422/
https://ncbi.nlm.nih.gov/pubmed/23411399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.01.028
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