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Chemoenzymatic synthesis and lectin recognition of a selectively fluorinated glycoprotein

A chemoenzymatic glycosylation remodeling method for the synthesis of selectively fluorinated glycoproteins is described. The method consists of chemical synthesis of a fluoroglycan oxazoline and its use as donor substrate for endoglycosidase (ENGase)-catalyzed transglycosylation to a GlcNAc-protein...

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Bibliographic Details
Main Authors: Orwenyo, Jared, Huang, Wei, Wang, Lai-Xi
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722283/
https://ncbi.nlm.nih.gov/pubmed/23566760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.03.009
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