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Expeditious Chemoenzymatic Synthesis of Homogeneous N-Glycoproteins Carrying Defined Oligosaccharide Ligands

An efficient chemoenzymatic method for the construction of homogeneous N-glycoproteins was described that explores the transglycosylation activity of the endo-β-N-acetylglucosaminidase from Arthrobacter protophormiae (Endo-A) with synthetic sugar oxazolines as the donor substrates. First, an array o...

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Autors principals: Ochiai, Hirofumi, Huang, Wei, Wang, Lai-Xi
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662341/
https://ncbi.nlm.nih.gov/pubmed/18803385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805044x
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