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CRISPRTarget: Bioinformatic prediction and analysis of crRNA targets

The bacterial and archaeal CRISPR/Cas adaptive immune system targets specific protospacer nucleotide sequences in invading organisms. This requires base pairing between processed CRISPR RNA and the target protospacer. For type I and II CRISPR/Cas systems, protospacer adjacent motifs (PAM) are essent...

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Autors principals: Biswas, Ambarish, Gagnon, Joshua N., Brouns, Stan J.J., Fineran, Peter C., Brown, Chris M.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737339/
https://ncbi.nlm.nih.gov/pubmed/23492433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.24046
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