Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells

Exogenous ribonucleases are known to inhibit tumor growth via apoptosis induction in tumor cells, allowing to consider them as promising anticancer drugs for clinical application. In this work the antitumor potential of binase was evaluated in vivo and the mechanism of cytotoxic effect of binase on...

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Autori principali: Mironova, Nadezhda L., Petrushanko, Irina Y., Patutina, Olga A., Sen’kova, Aexandra V., Simonenko, Olga V., Mitkevich, Vladimir A., Markov, Oleg V., Zenkova, Marina A., Makarov, Alexander A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737314/
https://ncbi.nlm.nih.gov/pubmed/23759588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.25164
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