White Matter Imaging Helps Dissociate Tau from TDP-43 in Frontotemporal Lobar Degeneration

BACKGROUND: Frontotemporal lobar degeneration (FTLD) is most commonly associated with TAR-DNA binding protein (TDP-43) or tau pathology at autopsy, but there are no in vivo biomarkers reliably discriminating between sporadic cases. As disease-modifying treatments emerge, it is critical to accurately...

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Main Authors: McMillan, Corey T., Irwin, David J., Avants, Brian B., Powers, John, Cook, Philip A., Toledo, Jon B., Wood, Elisabeth M., Van Deerlin, Vivianna M., Lee, Virginia M.-Y., Trojanowski, John Q., Grossman, Murray
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737288/
https://ncbi.nlm.nih.gov/pubmed/23475817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp-2012-304418
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