Increased Glyoxalase-1 Levels in Fkbp5 Knockout Mice Caused by Glyoxalase-1 Gene Duplication

Fkbp5 is genetically linked to stress-related diseases. Fkbp5 knockout mice are available and widely used to explore the role of Fkbp5 in health and disease. We found that these mice carry a gene duplication of glyoxylase-1, which explains why glyoxylase-1 levels are increased in the Fkbp5 knockout...

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Bibliographic Details
Main Authors: Kollmannsberger, Lorenz K., Gassen, Nils C., Bultmann, Andrea, Hartmann, Jakob, Weber, Peter, Schmidt, Mathias V., Rein, Theo
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2013
Subjects:
Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737170/
https://ncbi.nlm.nih.gov/pubmed/23733890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.006445
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