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The Curcumin Analog EF24 Targets NF-κB and miRNA-21, and Has Potent Anticancer Activity In Vitro and In Vivo

EF24 is a curcumin analog that has improved anticancer activity over curcumin, but its therapeutic potential and mechanism of action is unknown, which is important to address as curcumin targets multiple signaling pathways. EF24 inhibits the NF-κB but not the JAK-STAT signaling pathway in DU145 huma...

詳細記述

保存先:
書誌詳細
主要な著者: Yang, Chuan He, Yue, Junming, Sims, Michelle, Pfeffer, Lawrence M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3737134/
https://ncbi.nlm.nih.gov/pubmed/23940701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071130
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