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The mechanism of sodium and substrate release from the binding pocket of vSGLT

Membrane co-transport proteins that utilize a 5-helix inverted repeat motif have recently emerged as one of the largest structural class of secondary active transporters(1,2). However, despite many structural advances there is no clear evidence as to how ion and substrate transport are coupled. Here...

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Detalhes bibliográficos
Main Authors: Watanabe, Akira, Choe, Seungho, Chaptal, Vincent, Rosenberg, John M., Wright, Ernest M., Grabe, Michael, Abramson, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736980/
https://ncbi.nlm.nih.gov/pubmed/21131949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09580
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