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The electrostatics of VDAC: implications for selectivity and gating
The voltage-dependent anion channel (VDAC) is the major pathway mediating the transfer of metabolites and ions across the mitochondrial outer membrane. Two hallmarks of the channel in the open state are high metabolite flux and anion selectivity, while the partially closed state blocks metabolites a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736979/ https://ncbi.nlm.nih.gov/pubmed/20005234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.12.006 |
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