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The crystal structure of mouse VDAC1 at 2.3 Å resolution reveals mechanistic insights into metabolite gating

The voltage-dependent anion channel (VDAC) constitutes the major pathway for the entry and exit of metabolites across the outer membrane of the mitochondria and can serve as a scaffold for molecules that modulate the organelle. We report the crystal structure of a β-barrel eukaryotic membrane protei...

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Detalhes bibliográficos
Main Authors: Ujwal, Rachna, Cascio, Duilio, Colletier, Jacques-Philippe, Faham, Salem, Zhang, Jun, Toro, Ligia, Ping, Peipei, Abramson, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584669/
https://ncbi.nlm.nih.gov/pubmed/18988731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809634105
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