PanIN-specific regulation of Wnt signaling by HIF2α during early pancreatic tumorigenesis

Hypoxia promotes angiogenesis, proliferation, invasion and metastasis of pancreatic cancer. Essentially all studies of the hypoxia pathway in pancreatic cancer research to date have focused on fully malignant tumors or cancer cell lines, but the potential role of HIFs in the progression of pre-malig...

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Huvudupphovsmän: Criscimanna, Angela, Duan, Li-Juan, Rhodes, Julie A., Fendrich, Volker, Wickline, Emily, Hartman, Douglas J., Monga, Satdarshan P.S., Lotze, Michael T., Gittes, George K., Fong, Guo-Hua, Esni, Farzad
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736839/
https://ncbi.nlm.nih.gov/pubmed/23749643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0566
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