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Membrane Fusion: Grappling with SNARE and SM Proteins

The two universally required components of the intracellular membrane fusion machinery, SNARE and SM (Sec1/Munc18-like) proteins, play complementary roles in fusion. Vesicular and target membrane-localized SNARE proteins zipper up into an α-helical bundle that pulls the two membranes tightly togethe...

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Bibliographic Details
Main Authors: Südhof, Thomas C., Rothman, James E.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736821/
https://ncbi.nlm.nih.gov/pubmed/19164740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1161748
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