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Heat shock proteins attenuate SERCA inactivation by the anti-apoptotic protein Bcl-2: possible implications for the ER Ca(2+) mediated apoptosis
We had demonstrated that Bcl-2 and Bcl-2Δ21, a C-terminal truncated Bcl-2 sequence, inactivate SERCA1 in isolated sarcoplasmic reticulum (SR), accompanied by a translocation from caveolae-related domains of the SR. Here, we present evidence for the interaction of Bcl-2 with SERCA2b in C2C12 myoblast...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3736812/ https://ncbi.nlm.nih.gov/pubmed/22360692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111114 |
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