No Consistent Bioenergetic Defects in Presynaptic Nerve Terminals Isolated from Mouse Models of Alzheimer's Disease

Depressed cortical energy supply and impaired synaptic function are predominant associations of Alzheimer's disease (AD). To test the hypothesis that presynaptic bioenergetic deficits are associated with the progression of AD pathogenesis, we compared bioenergetic variables of cortical and hipp...

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Autors principals: Choi, Sung W., Gerencser, Akos A., Ng, Ryan, Flynn, James M., Melov, Simon, Danielson, Steven R., Gibson, Bradford W., Nicholls, David G., Bredesen, Dale E., Brand, Martin D.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2012
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736741/
https://ncbi.nlm.nih.gov/pubmed/23175831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2414-12.2012
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