No Consistent Bioenergetic Defects in Presynaptic Nerve Terminals Isolated from Mouse Models of Alzheimer's Disease

Depressed cortical energy supply and impaired synaptic function are predominant associations of Alzheimer's disease (AD). To test the hypothesis that presynaptic bioenergetic deficits are associated with the progression of AD pathogenesis, we compared bioenergetic variables of cortical and hipp...

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Detalhes bibliográficos
Main Authors: Choi, Sung W., Gerencser, Akos A., Ng, Ryan, Flynn, James M., Melov, Simon, Danielson, Steven R., Gibson, Bradford W., Nicholls, David G., Bredesen, Dale E., Brand, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736741/
https://ncbi.nlm.nih.gov/pubmed/23175831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2414-12.2012
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