The stimulation of CD8(+) T cells by dendritic cells pulsed with polyketal microparticles containing ion-paired protein antigen and poly(inosinic acid)–poly(cytidylic acid)

New adjuvants and delivery strategies are needed to optimize the ability of protein-based vaccines to elicit CD8(+) T cell responses. We have developed a model vaccine formulation containing ovalbumin (OVA) and the double-stranded RNA analog poly(inosinic acid)–poly(cytidylic acid) (poly(I:C)), a TL...

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Main Authors: Heffernan, Michael J., Kasturi, Sudhir P., Yang, Stephen C., Pulendran, Bali, Murthy, Niren
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3736733/
https://ncbi.nlm.nih.gov/pubmed/19036430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2008.10.034
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